HLP004

HLP004

 

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We present to you HLP004 (deuterated dimethyltryptamine (dDMT) and formerly as CYB004) :

HLP004, or HLP-004 is a serotonergic psychedelic related to dimethyltryptamine (DMT)  for the treatment of generalized anxiety disorder. It is administered by inhalation or intravenous injection. The drug is a tryptamine derivative and is a deuterated analogue and form of DMT.

The pharmacodynamic profile of HLP004, including its interactions with serotonin receptors and its effects in animals, is similar to that of DMT. As with DMT, HLP004 is a potent agonist of the serotonin 5-HT2A receptor and produces psychedelic-like effects in animals.

However, HLP004, due to its deuteration, is more resistant to metabolism than DMT and shows a longer elimination half-life (by 2.5- to 2.9-fold) and slower clearance (by 38 to 55%) in animals. The brain to plasma ratio of HLP004 was also increased (by 30%) relative to DMT, indicating slightly greater central permeability as well.

The pharmacokinetics and effects of HLP004 in humans have been studied and compared with those of DMT. Its elimination half-life was 37 to 40 minutes and its duration was approximately 40 minutes. For comparison, the half-life of DMT in humans has been reported to be 9 to 12 minutes (range 5–19 minutes).

HLP004 produced more robust psychedelic effects than DMT at lower concentrations. Additional details on the pharmacokinetics of HLP004 in humans have also been reported.

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You can buy HLP004 with a purity of 98%>! Buy HLP004 in our store without any problems. The product is intended for research purposes only and is not sold for consumption purposes.

By ordering / purchasing HLP004 you automatically agree to our general terms and conditions that you only purchase the product for research purposes and that you do not use the product for other purposes.

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